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DCAF13 Rabbit pAb (bs-9395R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-9395R
英文名稱 DCAF13 Rabbit pAb
中文名稱 DCAF13蛋白抗體
別    名 DCA13_HUMAN; DCAF13; DDB1 and CUL4 associated factor 13; DDB1-and CUL4-associated factor 13; DKFZP564O0463; GM83; HSPC064; WD repeat and SOF domain-containing protein 1; WD repeats and SOF1 domain containing; WDSOF1.  
研究領(lǐng)域 細胞生物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 51 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DCAF13: 301-400/445 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Function:
Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Subunit:
Interacts with DDB1.

Subcellular Location:
Nucleus, nucleolus (By similarity).

Similarity:
Contains 7 WD repeats.

SWISS:
Q9NV06

Gene ID:
25879

Database links:

Entrez Gene: 25879 Human

Entrez Gene: 223499 Mouse

Entrez Gene: 100173913 Orangutan

SwissProt: Q5ZLK1 Chicken

SwissProt: Q9NV06 Human

SwissProt: Q6PAC3 Mouse

SwissProt: Q5R4T8 Orangutan

Unigene: 532265 Human

Unigene: 321937 Mouse



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